NAD+ 500mg

Description:

Nicotinamide adenine dinucleotide (NAD+) is a coenzyme that plays a crucial role in various cellular processes, particularly in energy metabolism. It is composed of two nucleotides: nicotinamide (a form of vitamin B3 or niacin) and adenine (one of the four DNA bases). Research on NAD+ has gained significant attention due to its potential implications in aging and age-related diseases. NAD+ levels have been found to decline with age, and boosting NAD+ levels through supplementation or activation of NAD+-related pathways has shown promising effects in animal studies, including improved metabolic health and extended lifespan. Studies have also indicated that NAD+ exhibits potential benefits in enhancing muscle function, safeguarding nervous system cells, and mitigating the overall impact of aging.

NAD+ Research:

In recent years, there has been growing interest in NAD+ research due to its involvement in aging and age-related diseases. Here are some key areas of NAD+ research:

• NAD+ and Aging: NAD+ levels decline with age, and this decline is thought to contribute to the aging process. Researchers are studying ways to boost NAD+ levels in the body to potentially slow down aging and age-related diseases. One approach is through the use of NAD+ precursors such as nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), which can increase NAD+ levels in cells.
• NAD+ and Sirtuins: NAD+ is an essential cofactor for sirtuins, a class of proteins that play a role in regulating cellular processes related to aging and longevity. By activating sirtuins, NAD+ may help promote cellular health and longevity.
• NAD+ and Metabolism: NAD+ is involved in energy metabolism, particularly in the mitochondria, the cellular powerhouses. NAD+ participates in key metabolic pathways, such as glycolysis and oxidative phosphorylation. Research is focused on understanding the role of NAD+ in metabolic disorders like obesity, diabetes, and metabolic syndrome.
• NAD+ and DNA Repair: NAD+ is required for DNA repair enzymes called poly(ADP-ribose) polymerases (PARPs). These enzymes play a vital role in maintaining genomic stability and repairing DNA damage. Research suggests that enhancing NAD+ levels may improve DNA repair capacity and potentially reduce the risk of cancer and other diseases associated with DNA damage.
• NAD+ and Neurodegenerative Diseases: Some neurodegenerative diseases, such as Parkinson’s and Alzheimer’s, involve mitochondrial dysfunction and energy deficits. NAD+ restoration strategies are being explored as potential therapeutic interventions for these conditions.
• NAD+ and Exercise Performance: NAD+ has been implicated in the regulation of exercise performance and endurance. Some studies have suggested that increasing NAD+ levels through supplementation may improve exercise capacity and skeletal muscle function.

High Performance Liquid Chromatography (HPLC)