SS-31 50mg

Description:

SS-31, also known as Elamipretide, is a mitochondria-targeted peptide developed to treat mitochondrial dysfunction. It is a small peptide that penetrates the mitochondrial membrane and selectively targets cardiolipin, a lipid unique to the inner mitochondrial membrane. By interacting with cardiolipin, SS-31 stabilizes the mitochondrial membrane, reduces oxidative stress, and improves mitochondrial function. This peptide is being researched for its potential therapeutic effects in a variety of conditions related to mitochondrial dysfunction, including cardiovascular diseases, neurodegenerative diseases, and age-related muscle loss.

SS-31 Research:

SS-31 (Elamipretide) has been the subject of numerous research studies due to its potential therapeutic benefits in conditions related to mitochondrial dysfunction. Here are some notable research findings:

1. Cardiovascular Diseases:
   • Heart Failure: Studies have shown that SS-31 can improve cardiac function and reduce heart damage in models of heart failure. For instance, a study published in the Journal of the American College of Cardiology demonstrated that SS-31 improved left ventricular function and reduced myocardial infarction size in animal models.
   • Ischemia-Reperfusion Injury: SS-31 has been found to reduce the extent of damage caused by ischemia-reperfusion injury, which occurs when blood supply returns to the tissue after a period of ischemia or lack of oxygen. This effect is primarily attributed to its ability to reduce oxidative stress and stabilize mitochondrial function.
2. Neurodegenerative Diseases:
   • Alzheimer’s Disease: Research published in the Journal of Alzheimer’s Disease indicated that SS-31 could mitigate mitochondrial dysfunction, reduce oxidative stress, and improve cognitive function in animal models of Alzheimer’s disease.
   • Parkinson’s Disease: Studies suggest that SS-31 can protect dopaminergic neurons, reduce mitochondrial dysfunction, and alleviate motor deficits in models of Parkinson’s disease.
3. Musculoskeletal Disorders:
   • Age-Related Muscle Loss (Sarcopenia): SS-31 has shown promise in improving muscle function and reducing muscle atrophy associated with aging. Research in the Aging Cell demonstrated that SS-31 improved muscle strength and mitochondrial function in aged mice.
   • Duchenne Muscular Dystrophy: Preliminary studies have indicated that SS-31 may improve muscle function and reduce muscle damage in animal models of Duchenne muscular dystrophy.
4. Metabolic Diseases:
   • Diabetes: SS-31 has been investigated for its potential to improve insulin sensitivity and reduce complications related to diabetes by protecting mitochondrial function and reducing oxidative stress.
5. Renal Diseases:
   • Chronic Kidney Disease: Research has shown that SS-31 can reduce mitochondrial damage, oxidative stress, and fibrosis in models of chronic kidney disease, potentially improving kidney function.